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Tryptase (purified antigen), from human lung, 59,700 mU/mg, 10 µg
Key Features and Details
Tryptase is a glycoprotein released from mast cells during anaphylaxis, which performs a number of functions including catalyzing the activation of complement C3, converting prostromelysin to stromelysin (MMP-3), and cleaving fibrinogen resulting in a loss of clotting potential. Human tryptase is a major secretory protease of human lung mast cells.
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PRODUCT DESCRIPTION
Tryptase is a glycoprotein released from mast cells during anaphylaxis, which performs a number of functions including catalyzing the activation of complement C3, converting prostromelysin to stromelysin (MMP-3), and cleaving fibrinogen resulting in a loss of clotting potential. Human tryptase is a major secretory protease of human lung mast cells.
Application Notes
Tryptase has been used in a study that purified and characterized recombinant rat mast cell protease 7 expressed in Pichia pastoris. Tryptase has also been used in a study to investigate drug allergies in mast cell disease.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Proteomics | Used in a study to investigate drug allergies in mast cell disease
SPECIFICATIONS
SKU: 0857047
Base Catalog Number: 57047
Concentration
: 0.24 mg/ml
Formulation Details
: Liquid | 0.05M NaOAc; pH 5.0; containing 1.0M NaCl
Protein or Enzyme Type
: Other Proteins, Enzymes Peptides
Source
: Human Lung
Specific Activity
: 59,700 mU/mg using n-benzoyl-Phe-Val-Arg-pNA as substrate.
Uniprot Number
: Q15661
Unit Definition
: One unit will hydrolyze one µM of N-benzoyl-Phe-Val-Arg-pNA per minute at 410 nm, pH 8.3, 25 °C. The assay uses 0.1M Tris buffer, pH 8.3. E,1%,280nm=30.3
