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L-Glutamic acid
Key Features and Details
L-Glutamic Acid
SYNONYMS: L-2-Aminopentanedioic acid; (S)-(+)-glutamic acid; L-Glu; Glu; (S)-2-Aminopentanedioic acid; a-aminoglutaric acid; 1-aminopropane-1,3- dicarboxylic acid; Glu; E
CAS: #
142-47-2
MOLECULAR FORMULA: C5H9NO4
MOLECULAR WEIGHT: 169.112 g/mol
BEILSTEIN REGISTRY No.: 1723801
EC No: 200-293-7
MDL No: MFCD00002634
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PRODUCT DESCRIPTION
L-Glutamic Acid
Application Notes
It is often used as a food additive and flavour enhancer in the form of its salt, known as monosodium glutamate (MSG). A glutamic acid derivative, poly-?-benzyl-L-glutamate (PBLG), is often used as an alignment medium to control the scale of the dipolar interactions observed. L-Glutamic acid is used in cell culture as a component of MEM non-essential amino acids solution. L-Glutamic acid has been used as a nitrogen source in the culture of Aspergillus fumigatus NRRL 2436 for fumagillin production. The competitive roles of L-glutamic acid and L-aspartic acid in the growth of Oenococcus oeni NCFB 1707 have been studied.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Neuroscience | Neurotransmission
SPECIFICATIONS
SKU: 02101793-CF
Base Catalog Number: 101793
Alternate Names: L-2-Aminopentanedioic acid; (S)-(+)-glutamic acid; L-Glu; Glu; (S)-2-Aminopentanedioic acid; a-aminoglutaric acid; 1-aminopropane-1,3- dicarboxylic acid; Glu; E
Beilstein Registration No
: 1723801
Biochemical Physiological Actions
: An excitatory amino acid neurotransmitter that is an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). Glutamate is a key compound in cellular metabolism. It is the most abundant excitatory neurotransmitter in the vertebrate nervous system. It also serves as the precursor for the synthesis of the inhibitory GABA in GABA-ergic neurons. This reaction is catalyzed by glutamate decarboxylase (GAD), which is most abundant in the cerebellum and pancreas.
Boiling Point
: 225 deg C (decomposes)
CAS
: #
142-47-2
Density
: 26.2 (saturated water solution at 20 deg C)
EC No
: 200-293-7
Format
: Powder, Free Acid
Isoelectric Point
: 3.08 (Lit.)
MDL No
: MFCD00002634
Melting Point
: 450° F (Decomposes) (NTP, 1992)
Molecular Formula
: C5H9NO4
Molecular Weight
: 169.112 g/mol
Optical Rotation: +25° to +35° (c=10, 2N HCl )
pH
: Between 6,7 and 7,2 (5 % solution)
pKa
: 2.10 (a-COOH), 9.47 (a-NH2), 4.07 (f-COOH) (Lit.)
PPE
: Eyeshields, Gloves, Respirator filter
Purity
: =99%
RTECS No
: LZ9700000
Solubility
: greater than or equal to 100 mg/mL at 68° F (NTP, 1992)
