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Chlorhexidine
Key Features and Details
Chlorhexidine
SYNONYMS: 1,6-Di(N-p-chlorophenyl- diguanido) hexane ; 1,6-Di(N-p-Chlorophenyldiguanido) hexane; 1,1'-Hexamethylene bis[5-(4- chlorophenyl) biguanide]
CAS: #
55-56-1
MOLECULAR FORMULA: C22H30Cl2N10
MOLECULAR WEIGHT: 505.452 g/mol
BEILSTEIN REGISTRY No.: 2826432
EC No: 200-238-7
MDL No: MFCD00009673
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PRODUCT DESCRIPTION
Chlorhexidine
Application Notes
An intermediate for the production of chlorhexidine salts which are used as an antiseptic and disinfectant agent. It is effective against a wide range of bacteria, some fungi and some viruses, and an agent for the prevention of gingivitis. Commercial ophthalmic products have used this agent to replace thimerosal as a preservative; however, it can cause skin irritation. It ia used in analytical standard for pharmaceuticals.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Antiseptic | Disinfectant agent | Chemical Synthesis
SPECIFICATIONS
SKU: 02191358-CF
Base Catalog Number: 191358
Alternate Names: 1,6-Di(N-p-chlorophenyl- diguanido) hexane ; 1,6-Di(N-p-Chlorophenyldiguanido) hexane; 1,1'-Hexamethylene bis[5-(4- chlorophenyl) biguanide]
Beilstein Registration No
: 2826432
CAS
: #
55-56-1
EC No
: 200-238-7
Format
: Powder
Hazard Statements
: H315-H319-H334-H335-H410
MDL No
: MFCD00009673
Melting Point
: 258-260
Molecular Formula
: C22H30Cl2N10
Molecular Weight
: 505.452 g/mol
PPE
: Dust mask , Eyeshields, Faceshields, Gloves
RTECS No
: DU1925000
Safety Symbol
: GHS07, GHS08, GHS09
Solubility
: Water Solubility800 mg/L (at 20 °C)
Sterilization of Solutions
: Dilute solutions of chlorhexidine (<1.0% w/v) may be sterilized by autoclaving at 115 °C for 30 minutes or at 121-123 °C for 15 minutes. Autoclaving of solutions greater than 1.0% can result in the formation of insoluble residues and is therefore unsuitable. If sterile solutions are required at such high concentrations, then filtration through a 0.22 um membrane filter is recommended. Dilute chlorhexidine solutions may be stored at room temperature, and a shelf life of at least 1 year can be expected, provided that the packaging is adequate. Prolonged exposure to high temperature or light is to be avoided because this can adversely affect the stability of chlorhexidine solutions. All dilute solutions to be stored should be either heat-treated (sterilized or pasteurized) or chemically preserved (4 % isopropanol or 7 % ethanol) to eliminate the possibility of microbial contamination. .
Vapor Pressure
: 1.98X10-14 mm Hg at 25 deg C (est)
