DEAE-dextran, chloride form

Deae-Dextran, Chloride Form Application Notes DEAE-Dextran is used in the development of sustained release protein delivery and nucleic acid transfection systems. The use of DEAE-Dextran as an efficient adjuvant in vaccine production is well established. For instance, DEAE-Dextran has been used for immunization of guinea pigs and swine with inactivated foot-and-mouth disease and rhesus monkeys with inactivated Venezulean equine encephalomyelitis virus, IVEE. The mechanism of action of DEAE-Dextran is not clear. The effect on the humoral response of rhesus monkeys to IVEE vaccine results in a typical IgM-IgG response. It has been speculated that DEAE-Dextran may cause a stimulation of the helper T-cell function in antibody synthesis. Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. Key Applications Enhances the uptake of proteins and nucleic acids into cells