1,10-Phenanthroline monohydrate, 1 g

o-Phenanthroline is a metal chelating agent that prevents the induction of chromosomal aberrations in streptozotocin-treated cells. Application Notes 1,10-Phenanthroline Monohydrate is a redox indicator and reagent for spectrophotometric assay of silver. It forms a complex with ferrous (iron II, Fe2+) ion; it can be used as an indicator in oxidation-reduction systems, in titrating ferrous salts. The product forms a complex with Fe2+, but not with Fe3+. NH2OH can be added to the solution to reduce the Fe3+ to Fe2+ for analysis of iron. The complex between iron (II) and 1,10-phenanthroline can be quantitated by its absorption at 510 nm. Also chelates other dilvalent metals. Due to the compound's strong UV absorbance, it may interfere with spectrophotometric assays. When complexed with copper, it possesses nuclease activity that has been used to study DNA-protein interactions. Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. Key Applications Redox indicator

Typical Working Concentration : Effective concentration is 1-10 mM (as a metallo-protease inhibitor or metal-activated proteases inhibitor)