(3-[[1-[[2-(Hydroxymethyl)-1-pyrolidinyl]carbonyl]-2-methyl-propyl]carbamoyl]octano-hydroxamic Acid)Inhibitor Of Aminopeptidase M And Leucine Aminopeptidase.Ref.: Umezawa, H., Et Al., J. Antibiot.,38: 1629, (1985).
Application Notes
Inhibits aminopeptidase M, N and leucine aminopeptidase. Inhibits mammalian collagenase, Ki = .14 mM. Displays antitumor activity in vitro and in vivo. Actinonin has also been used to improve antibacterial activity and antiobesity therapeutics.
Usage Statement
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