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Adenosine, =98%
Key Features and Details
Adenosine
SYNONYMS: 9- ß-D-Ribofuranosyladenine; Adenine riboside; Adenine-9-ß-D-ribofuranoside
CAS: #
58-61-7
MOLECULAR FORMULA: C10H13N5O4
MOLECULAR WEIGHT: 267.245 g/mol
BEILSTEIN REGISTRY No.: 93029
EC No: 200-389-9
MDL No: MFCD00005752
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PRODUCT DESCRIPTION
Adenosine
Application Notes
Adenosine is active in cardiovascular disorders. It is indicated in cases of angina pectoris on account of its property of increasing the coronary output and in cases of hypertension on account of its vasodilator action. It is also active on the peripheral circulation, dilating the capillary vessels. It has also been recommended in the treatment of agranulocytosis. It induces apoptosis in human leukemia HL-60 cells and also has anti-arrhythmic properties.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Treatment of cardiovascular disorders and agranulocytosis
SPECIFICATIONS
SKU: 02100199-CF
Base Catalog Number: 100199
Alternate Names: 9- ß-D-Ribofuranosyladenine; Adenine riboside; Adenine-9-ß-D-ribofuranoside
Beilstein Registration No
: 93029
Biochemical Physiological Actions
: Endogenous neurotransmitter at adenosine receptors. Cardioprotective effects may relate to activation of A1 adenosine receptors. The antiplatelet and anti-inflammatory actions of adenosine appear to be mediated via the A2 adenosine receptor. In contrast, adenosine appears to be a pro-inflammatory mediator in asthma and chronic obstructive pulmonary disease (COPD).
CAS
: #
58-61-7
EC No
: 200-389-9
Extinction Coefficient
: 15.4 (259 nm in 0.01 M PO4, pH 7)
Format
: Powder, Free Base
Hazard Statements
: H302-H313
MDL No
: MFCD00005752
Melting Point
: 500 to 518° F (NTP, 1992)
Molecular Formula
: C10H13N5O4
Molecular Weight
: 267.245 g/mol
Optical Rotation: a20/D -70 °, c = 2 in 5% NaOH (lit.)
pH
: pH = 4.5-7.5 (solution of 3 mg/mL adenosine and 9 mg/mL sodium chloride in water)
PPE
: Eyeshields, Gloves, respirator filter
Purity
: =98%
Refractive Index
: n20D 1.91 (Lit.)
RTECS No
: AU7175000
Solubility
: >40.1 [ug/mL]
UV Visible Absorbance
: ?max (1N HCl)-255 - 260 nm OD250/OD260 - 0.80 - 0.90 OD280/OD260 - 0.17 - 0.24
Vapor Pressure
: 6.0X10-15 mm Hg at 25 deg C (est)
