Glycoprotein with tetrameric structure. Avidin is a basic glycoprotein isolated from raw egg white. It exhibits high binding affinity for biotin and is capable of producing biotin deficiency in rats and chicks. It also occurs in the white portion of eggs and the oviducts of birds and amphibia. It is destroyed by cooking or irradiation.
Application Notes
Avidin egg white was used in an assay using functionalized xenon as a biosensor to detect biotin-avidin binding. Egg white was used at 80 nmol.
Egg white avidin has been used as a cross-linker for biotin-conjugated antibodies. The product has also been used as a blocking agent in ELISA applications.
Usage Statement
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