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BIOTRANS (+) has a pore surface populated by a high density of quarterly ammonium groups which make it strongly cationic. The positive surface charge is maintained in the range pH 3 to over pH 10 and promotes strong ionic binding of negatively charged proteins and nucleic acids. BIOTRANS (+) membrane is ideally suited to new rapid transfer techniques for nucleic acid which provide excellent levels of sensitivity (e.g. Alkaline Transfer Procedure ). In addition, the membrane’s immediate immobilization characteristics make it suitable for prolonged transfer procedures without the risk of nucleic acid diffusion from the membrane.