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Mitomycin C
Key Features and Details
Mitomycin C
SYNONYMS: Ametycin; 7-Amino-9-a-methoxymitosane; Mit-C; Mitocin-C; Mitomycinum; Mutamycin; Azirizino[2', 3': 3,4] pyrrolo [1,2-a] indole 4,7-dione-6-amino-1,1a, 2, 8, 8a, 8b-hexahydro- 8- (hydroxymethyl) 8a-methoxy-5-methyl carbamate
CAS: #
50-07-7
MOLECULAR FORMULA: C15H18N4O5
MOLECULAR WEIGHT: 334.332 g/mol
BEILSTEIN REGISTRY No.: 7231816
EC No: 200-008-6
MDL No: MFCD00078109
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PRODUCT DESCRIPTION
Mitomycin C
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Antibacterial agent
SPECIFICATIONS
SKU: 02100498-CF
Base Catalog Number: 100498
Alternate Names: Ametycin; 7-Amino-9-a-methoxymitosane; Mit-C; Mitocin-C; Mitomycinum; Mutamycin; Azirizino[2', 3': 3,4] pyrrolo [1,2-a] indole 4,7-dione-6-amino-1,1a, 2, 8, 8a, 8b-hexahydro- 8- (hydroxymethyl) 8a-methoxy-5-methyl carbamate
Beilstein Registration No
: 7231816
Biochemical Physiological Actions
: Inhibitor of DNA synthesis, nuclear division, and cancer cells. Antibacterial to gram positive, gram negative, acid-fast bacilli. Mitomycin C decomposes DNA in cancer cells by forming a complex with DNA and inhibits division of cancer cells by interfering with the biosynthesis of DNA.
Boiling Point
: 534 °C
CAS
: #
50-07-7
EC No
: 200-008-6
Extinction Coefficient
: EmM(367 nm) = 21.84 (water); EmM(357 nm) = 22.78 (methanol); E1%(216 nm) = 742 (methanol); E1%(360 nm) = 742 (methanol); E1%(560 nm) = 0.06 (methanol)(Lit.)
Format
: Powder
Formulation Details
: Contains 2 mg/vial of pure mitomycin C.
Grade
: Antibiotic Class
Hazard Statements
: H302-H351
MDL No
: MFCD00078109
Melting Point
: Above 680° F (EPA, 1998)
Molecular Formula
: C15H18N4O5
Molecular Weight
: 334.332 g/mol
pKa
: 3.2, 6.5(Lit.)
Potency
: 850 µg/mg minimum
RTECS No
: CN0700000
Safety Symbol
: GHS07, GHS08
