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Nystatin, phytopure
Key Features and Details
Number: 1400-61-9
SYNONYMS: Mycostatin;Fungicidin
CAS: #
1400-61-9
MOLECULAR FORMULA: C
47
H
75
NO
17
MOLECULAR WEIGHT: 926.10
EC No: 215-749-0
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PRODUCT DESCRIPTION
A polyene antifungal effective against molds, fungi and yeast contamination. It binds to ergosterol and creates nystatin/ergosterol based ion channels in lipid bilayers causing K+ leakage that results in fungal cell death.
Application Notes
Nystatin is a polyene antibiotic. Its uses include preventing cell culture contamination and inducing interleukin (IL)-1, IL-8, and tumor necrosis factor a secretion in TLR2-expressing THP1 cells.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Antibiotic
SPECIFICATIONS
SKU: 02194534-CF
Base Catalog Number: 194534
Alternate Names: Mycostatin;Fungicidin
Biochemical Physiological Actions
: Mode of Action: Nystatin acts by binding to ergosterols in fungal cell membranes, increasing permeability of the membrane, and creating nystatin/ergosterol based ion channels. It also functions as a lipid raft-inhibiting reagent and as membrane associated cholesterol.Antimicrobial spectrum: Neomycin acts against fungi, yeasts and molds.
CAS
: #
1400-61-9
EC No
: 215-749-0
Format
: Powder
Grade
: Cell Culture
Molecular Formula
: C
47
H
75
NO
17
Molecular Weight
: 926.10
PPE
: Eyeshields, Gloves, Respirator filter
RTECS No
: RF5950000
Specific Activity
: >5000 u/mg
Typical Working Concentration
: 100 mg/L
UV Visible Absorbance
: 290, 305, 320 ± 2 nm( ? max (ethanol))
