Sodium Borohydride
Application Notes
Sodium borohydride has been used in the study of glycoprotein receptors. Cell monolayers were treated with sodium metaperiodate in sodium acetate to disrupt surface carbohydrates. Cells were then rinsed with PBS, and reduced with 50 mM sodium borohydride prepared in PBS (pH 7.4) for 30 minutes at room temperature. Nanocrystalline superlattices in gold colloid solution have been prepared by ligand-induction using AuCl3 reduced with sodium borohydride. Nucleophilic addition of hydride ion from sodium borohydride is an inexpensive alternative method for the Baylis-Hillman reaction to form [E]-a-methylcinnamic acids.
Usage Statement
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Key Applications
Chemical Synthesis | A strong reducing agent used in organic and biochemical reactions