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Streptomycin sulfate
Key Features and Details
Streptomycin Sulfate
SYNONYMS: Streptomycin Sesquisulfate; O-2-Deoxy-2-(methylamino)-a-L- glucopyranosyl-(1->2)-O-5-deoxy-3-C-formyl-a-L- lyxofuranosyl- (1->4)- N,N'- bis(aminoiminomethyl)-D-streptamine; Streptomycin A
CAS: #
3810-74-0
MOLECULAR FORMULA: C42H84N14O36S3
MOLECULAR WEIGHT: 1457.376 g/mol
BEILSTEIN REGISTRY No.: 3894995
EC No: 223-286-0
MDL No: MFCD00037023
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PRODUCT DESCRIPTION
Streptomycin Sulfate
Application Notes
Streptomycin Sulfate is used to inhibit bacterial protein synthesis at the level of initiation inhibition. It inhibits gram-negative and gram-positive bacteria.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Antibiotic
SPECIFICATIONS
SKU: 02100556-CF
Base Catalog Number: 100556
Alternate Names: Streptomycin Sesquisulfate; O-2-Deoxy-2-(methylamino)-a-L- glucopyranosyl-(1->2)-O-5-deoxy-3-C-formyl-a-L- lyxofuranosyl- (1->4)- N,N'- bis(aminoiminomethyl)-D-streptamine; Streptomycin A
Beilstein Registration No
: 3894995
Biochemical Physiological Actions
: Mode of Action: Inhibits prokaryote protein synthesis. Binds to S12 protein of 30S ribosomal subunit, preventing the transition from initiation complex to chain-elongating ribosome, causing miscoding or inhibiting initiation. Mode of Resistance: Mutation in rpsL (gene for S12 ribosomal protein) prevents binding of streptomycin to ribosome. Aminoglycoside phosphotransferase also inactivates. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
CAS
: #
3810-74-0
EC No
: 223-286-0
Format
: Powder
Half Life
: half-life in plasma is about 2-4 hours
Hazard Statements
: H302-H361
MDL No
: MFCD00037023
Molecular Formula
: C42H84N14O36S3
Molecular Weight
: 1457.376 g/mol
Optical Rotation: -77 to -79 ° (c=1% in H2O, 25 °C) (lit.)
PPE
: Dust mask, Eyeshields, Faceshields, Gloves
RTECS No
: WK4990000
Safety Symbol
: GHS07, GHS08
Solubility
: greater than or equal to 0.1 mg/mL at 64° F (NTP, 1992)
Specific Activity
: =650 u/mg
Typical Working Concentration
: Typically used at a concentration of 50-100 mg/liter
