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Thiamphenicol
Key Features and Details
Thiamphenicol
SYNONYMS: D -threo-2,2-dichloro-N-[ ß-hydroxy-a-(hydroxymethyl)-p-(methyl- sulfonyl)phenethyl]-acetamide
CAS: #
15318-45-3
MOLECULAR FORMULA: C12H15Cl2NO5S
MOLECULAR WEIGHT: 356.214 g/mol
BEILSTEIN REGISTRY No.: 2819542
EC No: 239-355-3
MDL No: MFCD00467983
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PRODUCT DESCRIPTION
Thiamphenicol
Application Notes
Thiamphenicol is an antibiotic that has been used to treat chancroid in men and uncomplicated gonorrhea. It is used in studies of bacterial protein synthesis at the level of peptidyl transferase activity associated with the 23S rRNA of the 50S ribosomal subunit. It is used to study chloraniphenicol-thiamphenicol-resistance and the use of fluorinated analogs when resistance is encountered. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Antibacterial | Antibiotics
SPECIFICATIONS
SKU: 02156846-CF
Base Catalog Number: 156846
Alternate Names: D -threo-2,2-dichloro-N-[ ß-hydroxy-a-(hydroxymethyl)-p-(methyl- sulfonyl)phenethyl]-acetamide
Beilstein Registration No
: 2819542
Biochemical Physiological Actions
: Thiamphenicol inhibits mitochondrial protein synthesis of proteins such as cytochrome c oxidase.
CAS
: #
15318-45-3
EC No
: 239-355-3
MDL No
: MFCD00467983
Molecular Formula
: C12H15Cl2NO5S
Molecular Weight
: 356.214 g/mol
PPE
: Eyeshields, Gloves, respirator filter
RTECS No
: AB6680000
Solubility
: >53.4 [ug/mL]
