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PRODUCT DESCRIPTION
Vitamin B12
Application Notes
Vitamin B12 plays a role in the synthesis of myelin. It is a cofactor for two enzymes, methionine synthase and L-methylmalonyl-CoA mutase. The compound is also used as an antipernicious anemia factor.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Antipernicious anemia factor | Cofactor | Treatment of vitamin B12 deficiency; cyanide poisoning; and hereditary deficiency of transcobalamin II
Biochemical Physiological Actions
: Biosynthesis of the basic structure of the vitamin is accomplished only by bacteria(which usually produce hydroxocobalamin). Bacteria-derived hydroxocobalamin (OHCbl) and CNCbl are converted in humans to useful coenzyme forms to support metabolic processes such as mitochondrial methylmalonylcoenzyme A mutase conversion of methylmalonic acid (MMA) to succinate to link lipid and carbohydrate metabolism, and activation of methionine synthase, the rate limiting step in the synthesis of methionine.
Boiling Point
: > 300 deg C
CAS
: #
68-19-9
EC No
: 200-680-0
Format
: Powder
MDL No
: MFCD00151092
Melting Point
: > 300 °C
Molecular Formula
: C63H88N14O14PCo
Molecular Weight
: 1355.388 g/mol
pH
: Commercially available cyanocobalamin for injection has a pH of 4.5-7