NucleoBond AXG columns are anion-exchange columns for isolating ultra-pure genomic DNA from tissue, bacteria, or yeast. Macherey-Nagel offers buffer sets for extracting genomic DNA from tissue and bacteria, which include all required buffers and enzymes (Proteinase K and RNase A). Using these buffer sets in combination with NucleoBond AXG columns allows isolation of up to 500 µg of genomic DNA from different matrices.